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. 2020 Dec 8;2020(12):MR000040. doi: 10.1002/14651858.MR000040.pub3

Comparison 5. Subgroup analyses for opinion pieces.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Different types of financial conflicts of interest 3   Risk Ratio (IV, Random, 95% CI) Subtotals only
5.1.1 Advisory board membership 2 103 Risk Ratio (IV, Random, 95% CI) 1.29 [0.58, 2.84]
5.1.2 Consultancy 2 156 Risk Ratio (IV, Random, 95% CI) 1.09 [0.52, 2.27]
5.1.3 Employment 2 132 Risk Ratio (IV, Random, 95% CI) 2.71 [0.03, 231.22]
5.1.4 Grants 3 210 Risk Ratio (IV, Random, 95% CI) 1.72 [0.86, 3.46]
5.1.5 Honoraria 2 132 Risk Ratio (IV, Random, 95% CI) 1.35 [0.35, 5.24]
5.1.6 Lecture or speaker fees 2 104 Risk Ratio (IV, Random, 95% CI) 1.88 [0.51, 6.94]
5.1.7 Other relationships 2 111 Risk Ratio (IV, Random, 95% CI) 0.96 [0.51, 1.83]
5.1.8 Stock ownership 2 107 Risk Ratio (IV, Random, 95% CI) 0.64 [0.22, 1.89]
5.2 Opinion pieces with major financial conflicts of interest versus opinion pieces with minor financial conflicts of interest 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
5.2.1 Major financial conflicts of interest 1 90 Risk Ratio (IV, Random, 95% CI) 9.43 [2.24, 39.62]
5.2.2 Minor financial conflicts of interest 1 56 Risk Ratio (IV, Random, 95% CI) 5.60 [0.38, 82.41]