| Study characteristics |
| Methods |
To examine the association between conflicts of interest and voting behaviour at the FDA advisory committee reports. Committee meetings on drugs and devices held between 2008 and 2014 |
| Data |
385 advisory committee reports |
| Comparisons |
Advisory committee members with financial conflicts of interest (defined as financial interests or personal and business relationships) and advisory committee members without financial conflicts of interest |
| Outcomes |
Recommendations (favourable recommendations defined as votes favourable to the product) |
| Funding source |
Funding source not described |
| Declaration of conflicts of interest |
The authors disclosed no conflicts of interest related any for‐profit company |
| Notes |
|
| Risk of bias |
| Item |
Authors' judgement |
Support for judgement |
| Adequate document inclusion process |
Unclear |
Not possible to determine |
| Adequate coding of conflicts of interest |
Unclear |
Not possible to determine |
| Adequate coding of recommendations |
Unclear |
Not possible to determine |
| Adequate dealing with confounding |
No |
Compared advisory committee reports of different drugs and devices |
