Skip to main content
. 2021 Apr 19;118(17):e2101818118. doi: 10.1073/pnas.2101818118

Fig. 2.

Fig. 2.

Peak neuropeptide release requires Ca2+ influx into terminals and IP3 signaling in the soma. (Ai) Peak release (ZT3) by UAS-Dilp2-FAP; Pdf-Gal4 s-LNv terminals is inhibited by Cd2+ (10 μM, n = 13) compared to controls (n = 14). **P < 0.01, unpaired t test. ii Peak release (ZT 23) by s-LNv somas is not affected by Cd2+ (10 μM, n = 13). For CON, n = 14). P = 0.8493, unpaired t test. (Bi) Peak release (ZT23) by l-LNv terminals is inhibited by Cd2+ (10 μM, n = 10) compared to controls (n = 8). **P < 0.01, unpaired t test. ii Peak release (ZT 23) by l-LNv somas is not affected by Cd2+ (10 μM, n = 10). For CON, n = 8). P = 0.8493, unpaired t test. (Ci) Peak release (ZT3) by s-LNv terminals is not different between Xestospongin C (20 μM, n = 9) and control terminals (CON, n = 12). P = 0.7951, unpaired t test. ii Peak release (ZT23) by s-LNv somas is significantly reduced by Xestospongin C (20 μM, n = 19) compared to controls (CON, n = 24). *P < 0.05, unpaired t test. (Di) Peak release (ZT23) by l-LNv terminals is not different between Xestospongin C (20 μM, n = 9) and controls (CON, n = 16). P = 0.3126, unpaired t test. ii Peak release (ZT 23) by l-LNv somas is reduced by Xestospongin C (20 μM, n = 16) compared to controls (CON, n = 21). **P < 0.01, unpaired t test.