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CIU data for monomeric PMP22. (A) Analysis of 9+ monomer WT PMP22 and all mutant PMP22 forms tested identify two features between 5 and 45 V. Fitting a sigmoid to these features allows for CIU50 determinations. (B) CIU50 values recorded for monomeric WT and mutant PMP22, n = 3, ordered by the disease phenotype severity engendered by the indicated mutant with SD shown as error bars.
