General practitioners' ratings of symptoms
Study	Outcomes	Notes
Grande 1999	Pain, mean (standard deviation (SD))a Intervention group: 2.03 (0.73), 130 participants; control group: 2.35 (0.95), 31 participants Nausea/vomiting, mean (SD)a Intervention group: 1.78 (0.82), 129 participants; control group: 2.00 (1.02), 30 participants Constipation, mean (SD)a Intervention group: 1.81 (0.78), 127 participants; control group: 1.97 (0.94), 29 participants Diarrhoea, mean (SD)a Intervention group: 1.17 (0.49), 127 participants; control group: 1.36 (0.73), 29 participants Breathlessness, mean (SD)a Intervention group: 1.82 (1.01), 129 participants; control group: 1.66 (0.93), 29 participants Anxiety, mean (SD) Intervention group: 2.10 (0.95), 127 participants; control group: 2.50 (0.97), 30 participants; P < 0.05 Depression, mean (SD) Intervention group: 1.62 (0.76), 125 participants; control group: 2.19 (1.08), 27 participants; P < 0.01	Intention‐to‐treat analysis 4‐point scale completed by the general practitioner. Lower score indicated less of a problem. No difference detected for ratings reported by district nurses and informal caregivers. Patients at home only. aAuthors reported not statistically significant.