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. 2021 Apr 22;2021(4):CD013495. doi: 10.1002/14651858.CD013495.pub2

Comparison 5. Subgroup indication, tapering versus continuation.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Relapse (HR) 13   Hazard Ratio (IV, Random, 95% CI) Subtotals only
5.1.1 No co‐intervention long‐term follow‐up (≥ 24 weeks) 13   Hazard Ratio (IV, Random, 95% CI) 2.97 [2.24, 3.93]
5.1.2 Subgroup Indication ‐ depressive disorder 10   Hazard Ratio (IV, Random, 95% CI) 2.62 [2.01, 3.42]
5.1.3 Subgroup Indication‐ anxiety disorder 3   Hazard Ratio (IV, Random, 95% CI) 7.06 [3.22, 15.52]