4.

Composite convergence outcome: achieved normal and improved NPC and PFV: NPC is normal (<6cm) and has improved by ≥4cm; PFV is normal (passing Sheard's criterion and a PFV break > 15 ∆) and has improved ≥ 10 ∆.

The certainty of evidence was rated 'high' if all domains were of 'no concerns.' The certainty of evidence was rated 'moderate' if two or more domains were of 'some concerns.'

The certainty of evidence was rated 'low' if two or more domains were of 'major concerns' or one domain of 'major concerns' plus one domain of 'some concerns.'

CI: confidence interval.