Skip to main content
. 2020 Dec 2;2020(12):CD006768. doi: 10.1002/14651858.CD006768.pub3

3. Network meta‐analysis results: children.

Outcome Mean rank Interventions
Treatment success defined as achieving both normal and improved NPC and PFV
RR (95% CI)
1.0 Office‐based vergence/accommodative therapy with home reinforcement      
2.1 1.96 (1.32, 2.94); high‐certainty evidence Home‐based computer vergence/accommodative therapy    
3.3 2.86 (1.82, 4.35); high‐certainty evidence 1.44 (0.93, 2.24); low‐certainty evidence Home‐based pencil/target push‐ups  
3.6 3.04 (2.32, 3.98); high‐certainty evidence 1.55 (1.00, 2.41); moderate‐certainty evidence 1.08 (0.66, 1.74); low‐certainty evidence Placebo intervention
Treatment success defined as achieving normal and improved NPC, PFV, and CISS
RR (95% CI)
1.0 Office‐based vergence/accommodative therapy with home reinforcement      
3.4 4.65 (1.23, 17.54); low‐certainty evidence Home‐based computer vergence/accommodative therapy    
3.1 4.41 (1.26, 15.38); low‐certainty evidence 0.95 (0.29, 3.07); low‐certainty evidence Home‐based pencil/target push‐ups  
2.5 5.12 (2.01, 13.07); moderate‐certainty evidence 1.10 (0.28, 4.40); low‐certainty evidence 1.16 (0.31, 4.35); low‐certainty evidence Placebo intervention
NPC
MD (95% CI)
1.0 Office‐based vergence/accommodative therapy with home reinforcement      
2.1 2.08 (0.11, 4.06) Home‐based computer vergence/accommodative therapy    
3.0 3.43 (1.46, 5.40) 1.35 (‐0.57, 3.27) Home‐based pencil/target push‐ups  
3.9 5.01 (3.56, 6.46) 2.93 (1.03, 4.83) 1.58 (‐0.33, 3.49) Placebo intervention
PFV
MD (95% CI)
1.0 Office‐based vergence/accommodative therapy with home reinforcement      
2.0 8.51 (5.67, 11.35) Home‐based computer vergence/accommodative therapy    
3.3 13.10 (10.42, 15.78) 4.58 (2.17, 6.99) Home‐based pencil/target push‐ups  
3.7 13.78 (11.41, 16.14) 5.26 (2.72, 7.81) 0.68 (‐1.67, 3.04) Placebo intervention
CISS score
MD (95% CI)
1.0 Office‐based vergence/accommodative therapy with home reinforcement      
3.0 8.63 (1.84, 15.42) Home‐based computer vergence/accommodative therapy    
3.5 9.92 (3.72, 16.12) 1.29 (‐4.74, 7.32) Home‐based pencil/target push‐ups  
2.4 6.79 (1.21, 12.36) ‐1.84 (‐7.95, 4.27) ‐3.13 (‐8.65, 2.38) Placebo intervention

CI: confidence interval; CISS: Convergence Insufficiency Symptom Survey; MD: mean difference; NPC: near point of convergence; PFV: positive fusional vergence; RR: risk ratio

Values in cells equal improvement (or risk) in column‐defining intervention, minus (or divided by) improvement (or risk) in row‐defining intervention; a MD greater than zero or a RR greater than 1 indicates greater improvement in column‐defining intervention. We used the Confidence in Network Meta‐Analysis (CINeMA) framework for evaluating the certainty of evidence for our primary outcome of 'treatment success' (see Figure 4 and Figure 5).