. 2020 Dec 2;2020(12):CD006768. doi: 10.1002/14651858.CD006768.pub3

4. Pairwise meta‐analysis or individual study results: adults.

Pairwise comparison	Number of RCTs	Improvement in NPC (MD with 95% CI); I²	Improvement in PFV (MD with 95% CI); I²	Improvement in CISS score (MD with 95% CI); I²
Office‐based vergence/accommodative therapy alone vs Office‐based vergence/accommodative therapy with home reinforcement	1	0.90 (‐2.03, 3.83); ‐	‐3.80 (‐7.53, ‐0.07); ‐	0.20 (‐2.84, 3.24); ‐
Office‐based vergence/accommodative therapy with home reinforcement vs Placebo intervention	2	2.43 (‐0.02, 4.87); 0.0%	16.73 (7.11, 26.36); 56.3%	3.03 (‐6.33, 12.39); 0.0%
Home‐based pencil/target push‐ups vs Placebo intervention	1	‐0.20 (‐6.38, 5.98); ‐	4.60 (‐3.66, 12.86); ‐	‐1.20 (‐11.13, 8.73); ‐
Home‐based pencil/target push‐ups vs Office‐based vergence/accommodative therapy with home reinforcement	1	‐2.80 (‐8.75, 3.15); ‐	‐7.80 (‐17.61, 2.01); ‐	‐4.70 (‐13.99, 4.59); ‐
Base‐in prism reading glasses vs Placebo intervention	1	0.4 (‐1.9, 2.7)*; ‐	0.0 (‐1.3, 1.2)*; ‐	‐8.9 (‐11.6, ‐6.3)*; ‐

CI: confidence interval; CISS: Convergence Insufficiency Symptom Survey; MD: mean difference; NPC: near point of convergence; PFV: positive fusional vergence; RCT: randomized controlled trial

*Difference in values measured at a follow up time point (instead of change from baseline)