Comparison 6. SENSITIVITY ‐ Wu2008a ‐ metformin vs placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
6.1 drop‐outs (12‐14 weeks)	2	94	Risk Ratio (IV, Random, 95% CI)	2.78 [0.08, 95.87]
6.2 fasting blood glucose (12‐14 weeks)	2	109	Mean Difference (IV, Random, 95% CI)	‐0.19 [‐0.46, 0.09]
6.2.1 Endpoint	2	109	Mean Difference (IV, Random, 95% CI)	‐0.19 [‐0.46, 0.09]
6.3 BMI (12‐14 weeks)	4	200	Mean Difference (IV, Random, 95% CI)	‐1.13 [‐1.86, ‐0.40]
6.3.1 Endpoint	2	109	Mean Difference (IV, Random, 95% CI)	‐0.83 [‐2.48, 0.82]
6.3.2 Change from baseline	2	91	Mean Difference (IV, Random, 95% CI)	‐1.20 [‐2.17, ‐0.23]
6.4 waist circumference (12‐14 weeks)	1	37	Mean Difference (IV, Random, 95% CI)	3.40 [‐1.99, 8.79]
6.4.1 Endpoint	1	37	Mean Difference (IV, Random, 95% CI)	3.40 [‐1.99, 8.79]