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. 2020 Nov 12;2020(11):CD013393. doi: 10.1002/14651858.CD013393.pub2

Hammoud 2014.

Study characteristics
Methods Study design: parallel RCT
Number of centers/setting: single center/not reported
Country: Egypt
Dates of the study: January 2010 to October 2012
Participants Total number of participants randomized: 96
  • tamsulosin group: 47

  • control group: 49


Age (mean, years):
  • tamsulosin group: 28.6 (SD 7.07)

  • control group: 29.5 (SD 7.04)


Sex (M/F):
  • tamsulosin group: 47/0

  • control group: 49/0


Stone location:
  • tamsulosin group: 35 renal/12 upper ureteral

  • control group: 33 renal/10 upper ureteral


Stone size (mean, mm):
  • tamsulosin group: 13 (SD 4.96)

  • control group: 12.3 (SD 4.82)


Inclusion criteria: males with solitary, radio‐opaque upper urinary tract stones, ≤ 20 mm in the maximum diameter
Exclusion criteria: not reported
Interventions Treatment group:
  • tamsulosin 0.4 mg/day

  • standard care: drink liberal fluids, analgesic PRN


Control group: control
SWL:
  • Lithotriptor: not reported

  • Power setting: not reported, interval: not reported

  • Number of shocks: max 3500, number of sessions: max 3; repeated at 2 week intervals

Outcomes Primary: stone clearance and analgesic dose
  • How measured: x‐ray

  • Time point measured: 2 weeks after last SWL session


Secondary: clearance rate, time to clearance
Subgroups: stone location (renal, upper ureteric), size (5–10 mm, 11–20 mm), timing (2, 4, 6, 8 weeks)
Funding sources None
Declarations of interest Not reported
Notes Language of publication: English
Type of publication: abstract only
Date of contact attempt with study authors: none
Contact status: N/A
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: method of random sequence generation unclear.
Allocation concealment (selection bias) Unclear risk Comment: unclear whether allocation was concealed.
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Comment: no placebo use described; participants likely not blinded.
Blinding of outcome assessment (detection bias)
Investigator assessed; susceptible (stone clearance, time to stone clearance) Unclear risk Comment: outcome assessors likely not blinded.
Blinding of outcome assessment (detection bias)
Investigator assessed; susceptible (major adverse events) Unclear risk Comment: outcome assessors likely not blinded.
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Comment: unable to assess what proportion of randomized participants were included in outcome analyses.
Selective reporting (reporting bias) Unclear risk Comment: no protocol available.
Other bias (additional SWL sessions) Unclear risk Comment: unclear whether > 1 SWL session was administered.