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. 2021 Apr 26;2021(4):CD010176. doi: 10.1002/14651858.CD010176.pub3

Madan 2014.

Study characteristics
Methods Trial design: randomised, split‐mouth trial
Location: Uttar Pradesh, India
Number of centres: single centre, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India
Recruitment period: not stated
Funding source: self‐funded
Participants Inclusion criteria: patients required extraction of non‐molar tooth and committed to replacement with dental implant after 6 months; systemically healthy, compliant
Exclusion criteria: systemic disease; radiographic bone height of < 7 mm at the site intended for surgery
Age at baseline: range 20 to 45 years
Gender: M 7/ F8
Smokers: 0
Teeth extracted: non‐molar teeth
Number randomised (participants/sites): 15/60
Number evaluated (participants/sites): 15/60
Interventions Comparison: ARP (grafting material) versus extraction alone
Test group: (n = 30 extraction sockets) resorbable polylactide and polyglycolide (PLA‐PGA) sponge (Fisiograft, Ghimas SpA, Italy)
Control group: (n = 30 extraction sockets) extraction alone
Surgical technique: flapless, no primary closure
Type of socket: 4‐wall socket
Duration of follow‐up: 6 months
Outcomes Width and height of alveolar ridge, histologic analyses
Method of assessment: periodontal probe, computed tomography, template
Notes Sample size calculation: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "Extraction sockets were randomly allocated for test and control groups by the toss of a coin into equal numbers"
Allocation concealment (selection bias) Unclear risk No information in the article
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk No information in the article
Incomplete outcome data (attrition bias)
All outcomes Low risk All data presented
Selective reporting (reporting bias) Low risk All outcomes appear to be reported
Other bias Low risk None detected