TABLE 2.

Positive and negative predictive values at 1%, 5%, and 10% seroprevalence for the quantitative Roche SARS-CoV-2 S assay

Parameter	Estimate (95% CI)
<14 Days Post-PCR Positivity
Sensitivity	67.1 (57.8–76.5)
Specificity	100 (100–100)
Seroprevalence
1%
PPV	100 (100–100)
NPV	99.7 (99.3–100)
5%
PPV	100 (100–100)
NPV	98.4 (97.6–99.2)
10%
PPV	100 (100–100)
NPV	96.8 (95.7–97.9)
≥14 Days Post-PCR Positivity
Sensitivity	82.5 (73.6–91.4)
Specificity	100 (100–100)
Seroprevalence
1%
PPV	100 (100–100)
NPV	99.8 (99.6–100)
5%
PPV	100 (100–100)
NPV	99.1 (98.6–99.7)
10%
PPV	100 (100–100)
NPV	98.3 (97.5–99.1)