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. 2021 Mar 19;59(4):e01295-20. doi: 10.1128/JCM.01295-20

TABLE 1.

Results from nonparametric statistical analysis of comparing known positive individual samples and the corresponding pools

Comparison Target Hodges-Lehman estimate of median CT value difference Distribution-free 95% confidence intervala
Individual (n = 8) vs 10-fold dilution in PBS (n = 8) N gene −3.47 (−1.07, −6.34)*
ORF1ab −3.08 (−0.65, −6.23)*
S gene −3.18 (−0.33, −6.06)*
Individual (n = 8) vs pool of 10 patient samples (n = 8) N gene −3.33 (−0.97, −5.77)*
ORF1ab −2.94 (−0.99, −5.63)*
S gene −3.18 (−1.05, −5.62)*
Individual (n = 8) vs pool of 5 patient samples (n = 8) N gene −3.09 (−0.99, −5.6)*
ORF1ab −2.76 (−0.5, −5.03)*
S gene −2.88 (−0.53, −5.21)*
a

*, P < 0.05 (Wilcoxon’s rank sum test).