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. 2021 May 3;16(5):e0250434. doi: 10.1371/journal.pone.0250434

Table 1. Summary characteristics of included studies.

Overall
(n = 206)
Africa
(n = 155)
Americas
(n = 11)
Asia
(n = 40)
p-value
Key Population (%)
MSM 56 (27.2) 11 (7.1) 10 (90.9) 35 (87.5) <0.001
FSW 25 (12.1) 21 (13.5) 0 (0.0) 4 (10.0) 0.371
HCW 23 (11.2) 20 (12.9) 1 (9.1) 2 (5.0) 0.358
Pregnant women 19 (9.2) 18 (11.6) 0 (0.0) 1 (2.5) 0.115
Transgender women 9 (4.4) 0 (0.0) 2 (18.2) 7 (17.5) <0.001
Teenagers 46 (22.3) 38 (24.5) 0 (0.0) 8 (20.0) 0.156
Type of Specimen (%) <0.001
Blood 21 (10.2) 9 (5.8) 1 (9.1) 11 (27.5)
Oral 99 (48.1) 88 (56.8) 5 (45.5) 6 (15.0)
Both 27 (13.1) 15 (9.7) 2 (18.2) 10 (25.0)
Not Specified 59 (28.6) 43 (27.7) 3 (27.3) 13 (32.5)
Type of Supervision (%) 0.012
Unsupervised 84 (40.8) 68 (43.9) 4 (36.4) 12 (30.0)
Supervised 14 (6.8) 6 (3.9) 0 (0.0) 8 (20.0)
Not Specified 83 (40.3) 60 (38.7) 6 (54.5) 17 (42.5)
Both supervision types 25 (12.1) 21 (13.5) 1 (9.1) 3 (7.5)
Type of Methods (%) 0.155
Mixed methods 23 (11.2) 21 (13.5) 0 (0.0) 2 (5.0)
Qualitative only 54 (26.2) 44 (28.4) 2 (18.2) 8 (20.0)
Quantitative only 129 (62.6) 90 (58.1) 9 (81.8) 30 (75.0)
Study Design (%) 0.546
Modelling 3 (1.5) 3 (1.9) 0 (0.0) 0 (0.0)
Observational 149 (72.3) 114 (73.5) 9 (81.8) 26 (65.0)
Interventional 54 (26.2) 38 (24.5) 2 (18.2) 14 (35.0)
    a) Quasi-experimental 32 (20.3) 18 (16.2) 2 (18.2) 12 (33.3)
    b) Randomized trial 22 (13.9) 20 (18.0) 0 (0.0) 2 (5.6)
Implementation Outcome (%)
Acceptability 122 (59.2) 93 (60.0) 10 (90.9) 19 (47.5) 0.032
Adoption 103 (50.0) 73 (47.1) 4 (36.4) 26 (65.0) 0.085
Appropriateness 56 (27.2) 46 (29.7) 1 (9.1) 9 (22.5) 0.253
Cost 16 (7.8) 15 (9.7) 0 (0.0) 1 (2.5) 0.195
Feasibility 24 (11.7) 20 (12.9) 1 (9.1) 3 (7.5) 0.614
Fidelity 23 (11.2) 17 (11.0) 1 (9.1) 5 (12.5) 0.939
Penetration 2 (1.0) 2 (1.3) 0 (0.0) 0 (0.0) 0.717
Sustainment 1 (0.5) 1 (0.6) 0 (0.0) 0 (0.0) 0.848
Linkage to Care 59 (28.6) 38 (24.5) 4 (36.4) 17 (42.5) 0.068
Safety 40 (19.4) 32 (20.6) 1 (9.1) 7 (17.5) 0.609

Notes: MSM–men who have sex with men, FSW–female sex worker, HCW–healthcare worker.