FIG 11.

Cytokine levels at day 7 in supernatants of CD4:CD8:NK coculture (ex vivo model). Each graph represents the expression levels for one cytokine. CD4:CD8:NK cocultures (green) had only cells without Gal-9 or an antibody against TIM-3 (anti-TIM-3). The addition of Gal-9 (2 nM) alone (orange) to the CD4:CD8:NK coculture was evaluated. No differences were observed in the levels of all cytokines analyzed after the addition of anti-TIM-3 without Gal-9 (blue) or with Gal-9 (pink) to the CD4:CD8:NK coculture.