FIG 4.

Galectin-9 (Gal-9) reverse HIV-1 latency in a cellular model based on IL-7. Bars show HIV-1 reactivation, expressed as p24 antigen production (n = 8). No significant differences were observed between p24 antigen concentrations with the positive control (PMA) and the different Gal-9 concentrations with or without an antibody against TIM-3 (anti-TIM-3). The comparison with the cellular model alone (Control) showed in all cases a significant difference in the p24 antigen values. Statistical significance was calculated using the Mann-Whitney U test. P values of <0.05 were considered statistically significant. *, P < 0.05; NS, not significant.