FIG 7.

Neutralization assay of MAbs against HBV/NL genotype C with VEM. Anti-HBs-S MAb 1 (A) or MAbs recognizing epitope I or III (B) were incubated with 20 GEq/cell of HBV/NL for 1 h and then infected into G2/NT-18 cells for 16 h. WT, wild-type. The luciferase activity of cells was determined at 7 days postinfection and is expressed relative to activity without antibodies. The concentration of antibody that results in 50% neutralization of HBV/NL infection (IC₅₀) was calculated and is shown. Data are averages of triplicate values, with error bars showing standard deviations.