TABLE 3.
Dissociation constants of MAbs recognizing epitopes I to III
| Epitope and MAb | KD (nM) | kon (M−1 s−1) | koff (s−1) |
|---|---|---|---|
| Epitope I | |||
| BP-L34 | 0.45 | 2.0E+05 | 8.7E−05 |
| BP-L41 | 2.2 | 4.5E+05 | 9.9E−04 |
| BP-G82 | <1.0E−03 | 4.0E+05 | <1.0E−07 |
| BP-G88 | <1.0E−03 | 2.4E+05 | <1.0E−07 |
| Epitope II | |||
| BP-L10 | 1.6 | 7.5E+05 | 1.2E−03 |
| BP-L16 | 1.5 | 5.3E+05 | 7.9E−04 |
| BP-L37 | 2.7E+02 | 1.6E+05 | 4.2E−02 |
| BP-G54 | 1.8 | 3.4E+05 | 6.1E−04 |
| BP-G91 | 1.3E+06 | 11 | 1.4E−02 |
| Epitope III | |||
| BP-L03 | <1.0E−03 | 3.66E+05 | <1.0E−07 |
| BP-L07 | <1.0E−03 | 1.36E+05 | <1.0E−07 |
| BP-L13 | <1.0E−03 | 1.43E+05 | <1.0E−07 |
| BP-G87 | <1.0E−03 | 7.33E+04 | <1.0E−07 |