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. 2021 Feb 10;95(5):e02190-20. doi: 10.1128/JVI.02190-20

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Copyright © 2021 Tavares et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

This article is made available via the PMC Open Access Subset for unrestricted noncommercial re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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FIG 3 — Distribution of well-defined RNA structures predicted for the HCV genome. The percentage of nucleotides in well-defined structured regions (high BPC/low Shannon) was calculated in 100-nt bins tiling HCV genomic sequence and is plotted as a function of the genomic coordinate (gray curve). Individual percentages of each genomic bin are also represented as a heatmap in the graph (color legend on the top right-hand corner). The locations of well-studied structural elements in the HCV genome are indicated with asterisks next to their respective genomic divisions, and details on each individual element are presented in Table 1.