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. 2021 Feb 10;95(5):e02190-20. doi: 10.1128/JVI.02190-20

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Copyright © 2021 Tavares et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

This article is made available via the PMC Open Access Subset for unrestricted noncommercial re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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FIG 6 — Comparison between in silico prediction in this study and experimental (in-cell SHAPE) structure reported by Huston et al. 2020 (32) for the ORF1ab region (including the 5′ UTR). The plots (gray lines) show the distribution of well-defined structure (percent high base pair content/low Shannon entropy) calculated in 100-nt bins tiling the ORF1ab region from both structural models. The same values are represented as a heat map in each graph to depict regions of high and low structural content according to the key shown on the upper right-hand corner. A cartoon with the genomic subdivisions of ORF1ab is shown to guide data visualization. The computed correlation coefficients between both data sets are shown in the table.