Box 1.

How to Use This Review

Review the entirety of this paper or jump to the applicable section according to individual discipline or work setting (eg, a nurse practicing in outpatient clinics may obtain the most benefit from the text and corresponding tables in the “ambulatory setting” section). Each row within the table outlines the various roles of clinicians in different care settings and indicates where overlap of practice and concepts exist. Consider the bottom line recommendation box a “call to action” on what the authors consider the most evidence-based area or idea worth exploring in future research on polypharmacy in older adults with cancer. Clinicians are encouraged to make simple changes and adopt what makes sense for their practice site. Applying all recommendations in a specific care setting may not be feasible initially.