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. 2021 Apr 29;14:2879–2892. doi: 10.2147/OTT.S299234

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© 2021 Chen et al.

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MiR-140-3p inhibits proliferation and promotes apoptosis by targeting BCL2.

Notes: (A) Transfection efficiency was determined by a qRT-PCR assay. (B) The viability of GC cells was detected by a CCK-8 assay. (C) An EdU assay was conducted to evaluate the proliferation of GC cells; overexpression of BCL2 reversed miR-140-3p-induced cell growth inhibition; scale bar = 100 μm. (D) Flow cytometric analysis was used to detect cell apoptosis. *P<0.05; **P<0.01; ***P<0.001.

Abbreviations: pc-NC, empty control vector; pc-BCL2-, BCL2-expressing vectors; min-NC, mimic negative control; inh-NC, inhibitor negative control.