TABLE 2.
MICs for CYP51 transformants
| Strain | MIC (μg/ml) ofa: |
|||||||
|---|---|---|---|---|---|---|---|---|
| AMB | TRB | CTZ | MCZ | FLZ | VRZ | KTZ | ITZ | |
| CBS 7982 | 4 | 2 | 4 | 4 | 1 | 0.03 | 0.03 | 0.03 |
| Y67F_4 | 8 | 2 | 4 | 16 | 1 | 0.008 | 0.06 | 0.125 |
| Y67F_8 | 4 | 2 | 4 | 4 | 2 | 0.015 | 0.06 | 0.125 |
| Y67F_10 | 8 | 2 | 8 | 4 | 1 | 0.015 | 0.06 | 0.03 |
| CBS 14141 | >32 | 32 | >256 | >256 | >256 | 4 | 0.06 | 0.06 |
| F67Y_1 | 4 | >32 | 256 | >256 | >256 | 4 | 0.25 | 0.125 |
| F67Y_3 | 4 | >32 | >256 | >256 | >256 | 4 | 0.5 | 2 |
| F67Y_4 | 4 | >32 | >256 | >256 | >256 | 16 | 0.5 | 0.25 |
a
AMB, amphotericin B; TRB, terbinafine; CTZ, clotrimazole; MCZ, miconazole; FLZ, fluconazole; VRZ, voriconazole; KTZ, ketoconazole; ITZ, itraconazole.