Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Characterization of M. abscessus EC/11770-resistant mutantsa
| Strain | Batch | MIC (μM)b |
||
|---|---|---|---|---|
| CLR | EC/11770 | LeuS mutations | ||
| M. abscessus Bamboo | 0.31 | 0.9 | None | |
| RM1 | 1 | 0.36 | >100 | LeuS A428P |
| RM2 | 1 | 0.38 | >100 | LeuS K502E |
| RM3 | 1 | 0.43 | 62 | LeuS V417M |
| RM4 | 2 | 0.42 | >100 | LeuS T327R |
| RM5 | 2 | 0.46 | 75 | LeuS V417M |
MIC values are the mean of two independent experiments.
CLR, clarithromycin.
