TABLE 2.
MIC/MEC values and cyp51A gene mutation type of four azole-resistant A. fumigatus isolates detected in this studya
| Isolate no. | MIC/MEC (mg/liter) |
Mutation in cyp51A | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Olo | Itra | Vori | Posa | Isa | AmB | Anid | Cas | Mica | ||
| 247-11 | 0.062 | >16 | 2* | 0.25* | 2* | 0.5 | 0.031 | 0.25 | 0.008 | WT |
| 247-20 | 0.031 | >16 | 2* | 0.25* | 2* | 0.5 | 0.016 | 0.25 | 0.008 | WT |
| 247-32 | 0.016 | >16 | 0.5 | 1 | 0.5 | 0.5 | 0.016 | 0.25 | 0.008 | G54V |
| 247-34 | 0.031 | >16 | 0.5 | 1 | >16 | 0.5 | 0.016 | 0.5 | 0.008 | TR34/L98H/S297T/F495I |
a
Abbreviations: amphotericin B, AmB; itraconazole, Itra; voriconazole, Vori; posaconazole, Posa; isavuconazole, Isa; olorofim, Olo; anidulafungin, Anid; caspofungin, Cas; micafungin, Mica. MICs are shown for amphotericin B, itraconazole, voriconazole, posaconazole, isavuconazole, olorofim; MECs are shown for anidulafungin, caspofungin, micafungin. Asterisks indicate values in the area of technical uncertainty.