. Author manuscript; available in PMC: 2021 May 3.

Published in final edited form as: Neurobiol Dis. 2019 Apr 2;127:432–448. doi: 10.1016/j.nbd.2019.02.015

Table 3.

Correlations between gene expression (mRNA levels) affected by curcumin. Coordinated changes in gene expression were evaluated by comparing two gene mRNA levels, or marker values [phosphotyrosine (PT) or TREM2:CD33 ratio], in conditions of control diet, Curc-Lo, or Curc-Hi.

Ratio of genes or markers
Treatment in Tg2576	TREM2: TYROBP	TREM2: CD68	TREM2: PT	iNOS: CD11b	Arg1: (TREM2:CD33)	Arg1: TYROBP
Control diet	0.64^***	0.77^**	n.s.	n.s.	n.s.	n.s.
Curcumin-Low (160 ppm)	0.98^**	0.98^**	0.96^**	+0.94^**	n.s.	+0.72^*
Curcumin-High (5000 ppm)	n.s.	n.s.	PT Not determined	n.s.	n.s.	−0.66^*

R2 values and statistical significance are shown in each cell for Pearson, 1-tailed correlations. Not significant (n.s.) p >

p < .05

^**

p < .01

^***

p < .001.