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. 2021 Apr 30;15(Suppl 1):26–39. doi: 10.14444/8053

Table 2.

Review of case series patient characteristics.

Parameter
Patient
1
2
3
Sex M M M
Age, y 55 35 34
Prior surgery No L4-5 microdiscectomy and laminectomy in 2015; revision in 2016 with postsurgical CSF leak No
Prior steroids Methylprednisolone dose pack 3 mo prior Corticosteroid epidural, date unknown Yes
Previous injection Lumbar facets with Regenokine Corticosteroid epidural, date unknown Yes, intradiscal LP-PRP twice
Injectate BMC BMC BMC
IV antibiotics Yes, cefazolin Yes, cefazolin Yes, cefazolin
Antibiotics in contrast Yes, 500 mcg gentamycin No No
Levels injected 2, L4-5, L5-S1 2, L3-5, L4-5 2, L4-5, L5-S1
Levels with complication 1, L5-S1 1, L3-4 1, L4-5
Confirmed pathogen No No, culture of fluid collection negative Yes, C acnes
ESR (mm/hr) 115.5 49 41
CRP (mg/L) 35 4.9 82.9
WBC (109/L) 8.6 6.3 7.3
Fever No Yes Yes
MRI findings Endplate edema Endplate edema Endplate edema
Treatment IV cloxacillin and oral rifampicin and moxifloxacin IV cefepime, ceftriaxone, and steroids IV ceftriaxone and oral amoxicillin
Outcome Clinical improvement Clinical improvement in pain after systemic steroids Persistent pain leading to consideration of surgical fusion

Abbreviations: BMC, bone marrow concentrate; CRP, C-reactive protein; CSF, cerebrospinal fluid; ESR, erythrocyte sedimentation rate; IV, intravenous; LP, leukocyte poor; MRI, magnetic resonance imaging; PRP, platelet-rich plasma; WBC, white blood cell count.