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. 2021 Apr 24;2021:9994004. doi: 10.1155/2021/9994004

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Copyright © 2021 BiKang Yang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

The PY-NLS motif is responsible for the nuclear import of FUBP1. (a) The cylinder shows the domain of the PY-NLS motif and function of FUBP1. Alignment revealing the FUBP1 PY-NLS motif from various mammalian species. (b) Immunoblots shows the FUBP1 and mutant levels in the nucleoplasm and cytoplasm of HEK-293 cell. (c) Immunoblots shows the PY-NLS and mutant levels in the nucleoplasm and cytoplasm. (d) Confocal microscopy of FUBP1 and mutant levels. (e) Confocal microscopy of PY-NLS and mutant levels. Scar bar 20 μm.