Figure 3.

Effects of camptothecin (CPT) on the inflammatory response of DSS-induced ulcerative colitis (UC) in mice. (a) Myeloperoxidase (MPO) activity assay. The protein levels of (b) IL-1β, (c) IL-6, and (d) TNF-α were detected using ELISA. Western blot assay of (e, f) inducible nitric oxide synthase (iNOS) and (e, g) cyclooxygenase-2 (COX-2). The relative protein levels were quantified by scanning densitometry and normalized to the protein level of β-actin. Values are presented as mean ± SD (^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗∗P < 0.0001 vs. the DSS group).