Table 4. Effect of zinc supplementation on frequency and periods of migraine attacks in patients with migraine attacks.
| Variable | Baseline | Treatment 2nd month | Treatment 3rd month | p value* | |||
|---|---|---|---|---|---|---|---|
| Time | Group | Time* group | |||||
| Frequency of migraine attacks (days) | 0.530 | 0.001 | < 0.001 | ||||
| Zinc group | 9.26 ± 6.09 | 7.69 ± 4.15 | 6.30 ± 2.67 | ||||
| Placebo group | 7.10 ± 3.99 | 7.50 ± 5.83 | 9.25 ± 5.18 | ||||
| Period of migraine attacks (hr) | 0.041 | < 0.001 | < 0.001 | ||||
| Zinc group | 10.50 ± 5.20 | 9.34 ± 4.37 | 8.84 ± 3.25 | ||||
| Placebo group | 7.85 ± 4.30 | 8.25 ± 4.02 | 8.28 ± 3.62 | ||||
Data are shown as mean ± standard deviation.
*Repeated measure analysis of variance were performed.