Table 1:
Demographic charcateristics by treatment arm
| Treatment Arm | ||||
|---|---|---|---|---|
| All | Placebo | Epo | ||
| n | 923 | 454 | 469 | p-value |
| Male, n (%) | 479 (51.9%) | 228 (50.2%) | 251 (53.5%) | 0.35 |
| Gestational age, n (%) | 0.07 | |||
| 24 weeks | 227 (24.6%) | 117 (25.8%) | 110 (23.5%) | |
| 25 weeks | 242 (26.2%) | 122 (26.9%) | 120 (25.6%) | |
| 26 weeks | 220 (23.8%) | 117 (25.8%) | 103 (22.0%) | |
| 27 weeks | 234 (25.4%) | 98 (21.6%) | 136 (29.0%) | |
| Birth weight (g), mean (sd) | 801.1 (187.9) | 793.2 (181.9) | 808.8 (193.4) | 0.21 |
| Birth length (cm), mean (sd) | 32.9 (2.9) | 32.8 (2.7) | 33 (3.1) | 0.47 |
| Size for Gestational Age | 0.55 | |||
| Large, n (%) | 104 (11.3%) | 50 (11.0%) | 54 (11.5%) | |
| Average, n (%) | 739 (80.1%) | 360 (79.3%) | 379 (80.8%) | |
| Small, n (%) | 80 (8.7%) | 44 (9.7%) | 36 (7.7%) | |
| Apgar 1 min, median (IQR) | 4 (2, 6) | 4 (2, 6) | 4 (2, 6) | 0.14 |
| Apgar 5 min, median (IQR) | 7 (5, 8) | 7 (5, 8) | 7 (5, 8) | 0.74 |
| OFC (cm), mean (sd) | 23.1 (1.9) | 23.1 (1.9) | 23.1 (1.9) | 0.71 |
| Number of festuses, median (IQR) | 1 (1, 2) | 1.3 (0.5) | 1.3 (0.6) | 0.67 |
| Prenatal steroids, n (%) | 831 (91.6%) | 407 (91.5%) | 424 (91.8%) | 0.84 |
| 1 dose, n (%) | 174 (20.9%) | 76 (18.7%) | 98 (23.1%) | 0.25 |
| 2 doses, n (%) | 575 (69.2%) | 289 (71.0%) | 286 (67.5%) | |
| 3 doses, n (%) | 74 (8.9%) | 39 (9.6%) | 35 (8.3%) | |
| Delivery room resuscitation, n (%) | ||||
| Any | 896 (97.1%) | 446 (98.2%) | 450 (95.9%) | 0.09 |
| Oxygen | 738 (80.0%) | 365 (80.4%) | 373 (79.5%) | 0.81 |
| Positive pressure | 797 (86.3%) | 403 (88.8%) | 394 (84.0%) | 0.04 |
| Intubation | 748 (81.0%) | 374 (82.4%) | 374 (79.7%) | 0.35 |
| Surfactant | 480 (52.0%) | 240 (52.9%) | 240 (51.2%) | 0.65 |
| Chest compression | 72 (7.8%) | 37 (8.1%) | 35 (7.5%) | 0.79 |
| Resuscitation drugs | 32 (3.5%) | 14 (3.1%) | 18 (3.8%) | 0.66 |