Table 1.
Enterogermina formulation, spore concentration and dose regimen
| Study name | Test or reference | Oral formulation | Spore concentration | Dose regimen | Name |
|---|---|---|---|---|---|
|
2012 EGKINETIC4 (EUDRACT 2010-023187-41) |
Test | Vial | 4 × 109 | OD | E4 OD |
| Reference | Vial | 2 × 109 | BID | E2 BID | |
|
2012 EGKINETIC6 (EUDRACT 2010-024497-19) |
Test | Powder for suspension | 6 × 109 | OD | ES6 OD |
| Reference | Capsule | 2 × 109 | TID | EC2 TID | |
|
2016 EGKINETIC6OP (EUDRACT 2015-003330-27) |
Test | Powder (no suspension) | 6 × 109 | OD | E6 OD |
| Reference | Powder for suspension | 6 × 109 | OD | ES6 OD |
BID twice daily, OD once daily, TID three times daily