Table 3.
Study name | Oral formulation | Name | Mean (± SD) spore forms count (millions), AUC0–t |
---|---|---|---|
2012 EGKINETIC4 | Vial 4 × 109 OD | E4 OD | 213.8 ± 60.2 |
Vial 2 × 109 BID | E2 BID | 270.7 ± 147.7 | |
2012 EGKINETIC6 | Powder 6 × 109 OD | ES6 OD | 319.0 ± 221.1 |
Capsule2 × 109 TID | EC2 TID | 312.7 ± 218.0 | |
2016 EGKINETIC6OP | Sachet 6 × 109 OD | E6 OD | 212.6 ± 118.0 |
Powder 6 × 109 OD | ES6 OD | 293.2 ± 247.2 |
Spore count in millions; AUC is per hour
AUC area under the curve; BID twice daily; OD once daily; TID three times daily