Table 4.
Results of 2-level and 3-level MLM analyses for the genotyped sample with PC covariate (N = 1375 twins in 714 families)
| Parameter | 2-Level model | 3-Level model |
|---|---|---|
| Intercept | ||
| Intercept (SE) | 128.5 (0.26) | 128.5 (0.26) |
| Covariates | ||
| βsex (SE) | − 0.74 (0.31) | − 0.74 (0.31) |
| βage (SE) | 1.16 (0.18) | 1.17 (0.18) |
| βPC1 (SE) | 0.11 (0.02) | 0.11 (0.02) |
| a, c, e, Region path loadings | ||
| a (SE) | 4.55 (0.20) | 4.55 (0.20) |
| c (SE) | 3.03 (0.36) | 3.03 (0.36) |
| e (SE) | 1.13 (0.04) | 1.13 (0.04)) |
| Region (SE) | 8.97 × 10−6 (0.76) | |
| Total variance (a2 + c2 + e2 (+ region2)) | 31.19 | 31.19 |
| A (standardized) | 0.664 | 0.664 |
| C (standardized) | 0.295 | 0.295 |
| E (standardized) | 0.041 | 0.041 |
| REGION (standardized) | 2.58 × 10−12 | |
Path coefficient estimates with standard errors (SE) and standardized variance components of the 2- and 3-level ACER model, including PC1