Table 2.

Patient baseline characteristics by age group

Age, years	n	Sex		Racea		Tumor type		ECOG PS scoreb		Median body weight, kg (range)	Median BSA, m2 (range)
		M	F	Asian	Non-Asian	GIST	Other	0	> 0
2–5	6	3	3	1	5	0	6	2	1	18.3 (16.2–28.7)	0.7 (0.7–1.0)
6–11	20	9	11	0	18	0	20	8	4	28.4 (17.1–56.3)	1.1 (0.7–1.5)
12–17	33	17	16	2	30	6	27	18	15	56 (37.1–100)	1.6 (1.3–2.1)
18–21	6	3	3	1	5	0	6	1	5	71.2 (62.5–74.5)	1.9 (1.6–1.9)
Total 6–17	53	26	27	2	48	6	47	26	19	49.1 (17.1–100)	1.4 (0.7–2.1)
Total 2–21	65	32	33	4	58	6	59	29	25	49.1 (16.2–100)	1.4 (0.7–2.1)

ECOG PS Eastern Cooperative Oncology Group performance status, F female, GIST gastrointestinal stromal tumor, M male

^aRace was unknown for three patients

^bECOG PS scores based on either the ECOG PS score or extrapolated from the Karnofsky Performance Status Scale, with ECOG PS scores set to 0 and 1 for Karnofsky Performance Status Scales > 90 and ≤ 90, respectively. The ECOG PS score could not be determined for 11 patients