Table 2.
Univariate and multivariable logistic regression analysis for the prediction of PNI status.
Characteristics | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
β | Odds ratio (95% CI lower–upper) | P value | β | Odds ratio (95% CI lower–upper) | P value | |
Age | − 0.019 | 0.982 (0.943–1.022) | 0.369 | – | – | – |
Gender | 0.693 | 2.000 (0.493–8.109) | 0.332 | – | – | – |
CEA (> 3.4 ng/ml) | 0.968 | 2.632 (0.888–7.794) | 0.081 | – | – | – |
CA19-9 (> 22 ng/ml) | − 1.609 | 0.200 (0.051–0.788) | 0.021 | − 2.133 | 0.118 (0.009–1.514) | 0.101 |
Tumor location | 0.395 | 1.484 (0.514–4.287) | 0.466 | – | – | – |
Tumor length | 0.062 | 1.064 (0.817–1.386) | 0.643 | – | – | – |
Tumor thickness | 0.607 | 1.834 (0.768–4.382) | 0.172 | – | – | – |
R_T staging | 1.270 | 3.562 (0.719–17.662) | 0.120 | – | – | – |
R_N staging | 1.030 | 2.800 (0.706–11.097) | 0.143 | – | – | – |
P_T staging | − 1.884 | 0.152 (0.031–0.735) | 0.019 | − 0.151 | 0.860 (0.086–8.606) | 0.898 |
P_N staging | − 2.007 | 0.134 (0.039–0.469) | 0.002 | − 2.404 | 0.09 (0.009–0.950) | 0.045 |
T2WI score | 2.662 | 14.331 (2.955–69.488) | 0.001 | 4.661 | 105.721 (3.091–3615.790) | 0.010 |
DWI score | 4.294 | 73.234 (0.841–6374.624) | 0.060 | 0.454 | 1.575 (0.001–2063.812) | 0.901 |
CT score | 1.889 | 6.615 (2.182–20.055) | 0.001 | 1.439 | 4.218 (1.070–16.620) | 0.040 |
β regression coefficient, 95% CI lower–upper, the lower value to the upper value of 95% confidence interval, CEA carcinoembryonic antigen, CA19-9 cancer antigen 19–9, R_T staging T staging was diagnosed based on rectal MR and CT images, R_N staging N staging was diagnosed based on rectal MR and CT images, P_T staging T staging was diagnosed by pathology, P_N staging N staging was diagnosed by pathology.