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. 2021 May 3;11:9429. doi: 10.1038/s41598-021-88831-2

Table 2.

Univariate and multivariable logistic regression analysis for the prediction of PNI status.

Characteristics Univariate analysis Multivariate analysis
β Odds ratio (95% CI lower–upper) P value β Odds ratio (95% CI lower–upper) P value
Age − 0.019 0.982 (0.943–1.022) 0.369
Gender 0.693 2.000 (0.493–8.109) 0.332
CEA (> 3.4 ng/ml) 0.968 2.632 (0.888–7.794) 0.081
CA19-9 (> 22 ng/ml) − 1.609 0.200 (0.051–0.788) 0.021 − 2.133 0.118 (0.009–1.514) 0.101
Tumor location 0.395 1.484 (0.514–4.287) 0.466
Tumor length 0.062 1.064 (0.817–1.386) 0.643
Tumor thickness 0.607 1.834 (0.768–4.382) 0.172
R_T staging 1.270 3.562 (0.719–17.662) 0.120
R_N staging 1.030 2.800 (0.706–11.097) 0.143
P_T staging − 1.884 0.152 (0.031–0.735) 0.019 − 0.151 0.860 (0.086–8.606) 0.898
P_N staging − 2.007 0.134 (0.039–0.469) 0.002 − 2.404 0.09 (0.009–0.950) 0.045
T2WI score 2.662 14.331 (2.955–69.488) 0.001 4.661 105.721 (3.091–3615.790) 0.010
DWI score 4.294 73.234 (0.841–6374.624) 0.060 0.454 1.575 (0.001–2063.812) 0.901
CT score 1.889 6.615 (2.182–20.055) 0.001 1.439 4.218 (1.070–16.620) 0.040

β regression coefficient, 95% CI lower–upper, the lower value to the upper value of 95% confidence interval, CEA carcinoembryonic antigen, CA19-9 cancer antigen 19–9, R_T staging T staging was diagnosed based on rectal MR and CT images, R_N staging N staging was diagnosed based on rectal MR and CT images, P_T staging T staging was diagnosed by pathology, P_N staging N staging was diagnosed by pathology.