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. 2021 May 3;12:2493. doi: 10.1038/s41467-021-22767-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Chord diagram presenting the 53 proteins with pQTLs related to clinical measurements. The size of the link is defined as the absolute value of coefficient of the corresponding effect (mixed-effect modeling analysis for each protein and clinical measurement adjusted for gender, age and visit). b A heatmap showing the top 50 proteins most strongly associated with clinical assays based on both wellness and T2D cohorts. Only proteins who are exclusive in the PEA-NGS are listed. See complete results of the pairwise Pearson correlation values between all proteins and clinical assays in Supplementary Data 7. Source data are provided as a Source Data file.