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. 2021 May 3;6:30. doi: 10.1038/s41525-021-00193-w

Table 2.

Gene Set Enrichment Analysis of KEGG metabolic pathways in 70 LMS classified into three molecular subtypes.

Gene set name ES NES FDR Number of genes in core enrichment
Subtype 1 KEGG Inositol phosphate metabolism 0.49 1.56 0.22 28/54
Subtype 2 KEGG Citrate cycle, TCA cycle 0.65 1.84 0.003 16/30
Subtype 2 KEGG Amino sugar and nucleotide sugar metabolism 0.53 1.58 0.05 28/43
Subtype 2 KEGG Glyoxylate and dicarboxylate metabolism 0.50 1.33 0.23 7/16
Subtype 3 KEGG Ascorbate and aldarate metabolism 0.49 1.379 0.16 15/25

ES enrichment score, NES normalized enrichment score, FDR false discovery rate.