Table 3.
Unadjusted and Adjusted Odds Ratios of Geriatric Assessment Domains, Health-Related Quality of Life, and Healthcare Utilization Based on Moderate/Severe Depression Status.
| Geriatric Assessment | Unadjusted Odds, 95% CI | Adjusted Odds*, 95% CI |
|---|---|---|
| ≥1 Fall | 3.71 (1.92-7.16) | 4.01 (1.94-8.26) |
| Impaired (≥2) ECOG Performance Status | 3.80 (2.00-7.22) | 3.76 (1.88-7.52) |
| Reported Limitations in Walking One Block | 5.72 (2.48-13.2) | 5.18 (2.15-12.4) |
| IADL Dependence | 6.33 (2.74-14.6) | 7.06 (2.91-17.1) |
| ADL Dependence | 5.24 (2.67-10.3) | 6.23 (2.89-13.4) |
| Moderate/Severe Cognitive Dysfunction | 22.4 (8.54-58.7) | 42.2 (11.2-159) |
| ≥3 Comorbidities other than cancer | 2.61 (1.32-5.15) | 2.69 (1.29-5.60) |
| ≥9 Daily Medications | 2.05 (1.06-3.95) | 2.51 (1.21-5.20) |
| Limitations in Social Activities | 4.75 (2.48-9.10) | 4.49 (2.20-9.18) |
| Malnutrition | 5.87 (2.53-13.6) | 5.86 (2.40-14.3) |
| Moderate/Severe Anxiety | 30.8 (13.9-68.6) | 58.9 (20.7-167) |
| Vision Impairment | 4.25 (2.22-8.12) | 5.07 (2.43-10.6) |
| Hearing Impairment | 2.04 (1.07-3.87) | 2.01 (0.97-4.16) |
| Moderate/Severe Fatigue | 12.9 (3.90-42.4) | 11.2 (3.31-37.6) |
| Moderate/Severe Pain | 4.51 (2.20-9.24) | 4.73 (2.12-10.5) |
| Frail | 12.5 (5.61-27.9) | 13.7 (5.80-32.1) |
| Financial Distress | 2.70 (1.12-6.51) | 1.89 (0.66-5.38) |
| Health-Related Quality of Life | ||
| Physical Health Score, <40 | 8.04 (3.70-17.4) | 7.58 (3.30-17.4) |
| Mental Health Score, <40 | 22.3 (9.47-52.3) | 26.3 (10.1-68.8) |
| Healthcare Utilization | ||
| ER Visit | 1.28 (0.66-2.51) | 1.29 (0.61-2.70) |
| Hospitalization | 1.96 (0.99-3.90) | 1.90 (0.90-4.04) |
*
Adjusted for Age, Sex, Education, Cancer Type, and Cancer Stage.