Table 5.

Independent predictors of outcomes in the studied cohort.

	OR	95%CI	p
Mortality by day 14§
NIHSS on admission	1.20	1.09–1.32	0.0001
INR	3.54	1.06–11.85	0.041
Mortality by day 90 (mRS 0–5 vs. mRS 6)#
NIHSS on admission	1.17	1.07–1.28	0.001
INR	2.02	0.71–5.75	0.190
mCLA 10%CLT <38.5 min	3.69	0.84–16.15	0.083
Unfavorable long-term outcome (mRS 0–1 vs. mRS 2–6)†
NIHSS on admission	1.57	1.21–2.05	0.001
mCLA 10%CLT <32.25 min	6.14	1.11–34.02	0.038

Last step of backward multiple regression analysis is provided.

^§Backward multiple regression model included age, sex, NIHSS on admission, hypertension, INR, platelet count, smoking status, hemorrhage volume, mCLA 10%CLT (threshold: <30.25 min).

^#Backward multiple regression model included age, sex, NIHSS on admission, hypertension, BMI, INR, platelet count, hemorrhage volume, mCLA 10%CLT (threshold: <38.5 min).

^†Backward multiple regression model included age, sex, NIHSS on admission, hypertension, BMI, INR, platelet count, hemorrhage volume, mCLA 10%CLT (threshold: <32.25 min).

95%CI, 95% confidence interval; 10%CLT, 10% clot lysis time; INR, international normalized ratio; mCLA, modified clot lysis assay performed in the presence of cell-free DNA and histones; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio.