Table 2.
Mean ± SEM of arterial blood-gas values, pH, lactate concentrations, total hemoglobin, base excess in horses with medetomidine isoflurane (group MED) or xylazine isoflurane (group XYL) balanced anesthesia.
| Parameter | Group | Time point | |||
|---|---|---|---|---|---|
| t30 | t60 | t90 | t150 | ||
| n MED | 31 | 30 | 26 | 8 | |
| n XYL | 27 | 27 | 26 | 10 | |
| PaCO2, mmHg (kPa) | MED | 50.57 ± 0.49 (6.7 ± 0.07) | 52.89 ± 0.51 (7.1 ± 0.07)*# | 54.82 ± 0.56 (7.3 ± 0.07)*# | 55.56 ± 1.10 (7.4 ± 0.15)# |
| XYL | 51.19 ± 0.52 (6.8 ± 0.07) | 51.03 ± 0.54 (6.8 ± 0.07)* | 52.11 ± 0.55 (6.9 ± 0.07)* | 52.45 ± 0.96 (7.0 ± 0.13) | |
| PaO2, mmHg (kPa) | MED | 153.97 ± 5.16 (20.5 ± 0.69) | 151.34 ± 5.45 (20.2 ± 0.73) | 146.47 ± 5.90 (19.5 ± 0.79) | 152.00 ± 11.40 (20.3 ± 1.52) |
| XYL | 151.03 ± 5.53 (20.1 ± 0.74) | 148.56 ± 5.53 (19.8 ± 0.79) | 155.82 ± 5.68 (20.8 ± 0.76) | 145.30 ± 10.00 (19.4 ± 1.33) | |
| pH | MED | 7.35 ± 0.003 | 7.35 ± 0.003 | 7.35 ± 0.003 | 7.36 ± 0.006 |
| XYL | 7.35 ± 0.003 | 7.36 ± 0.003 | 7.36 ± 0.003 | 7.38 ±0.006# | |
| Lactate (mmol L−1) | MED | 1.61 ± 0.03 | 1.83 ± 0.03# | 1.9 ± 0.03*# | 2.00 ± 0.06# |
| XYL | 1.47 ± 0.03 | 1.60 ± 0.03# | 1.65 ± 0.03*# | 1.56 ± 0.06# | |
| Hb (g dL−1) | MED | 11.32 ± 0.12 | 10.6 ± 0.12# | 10.40 ± 0.13# | 10.88 ± 0.25 |
| XYL | 11.62 ± 0.12 | 10.76 ± 0.13# | 10.35 ± 0.13# | 9.52 ± 0.24# | |
| BE (mmol L−1) | MED | 2.37 ± 0.20 | 2.00 ± 0.21# | 2.87 ± 0.23# | 4.55 ± 0.44# |
| XYL | 1.56 ± 0.21 | 2.10 ± 0.22 | 2.50 ± 0.22# | 4.05 ± 0.39# | |
Significant differences (p < 0.05) between groups are indicated by
*
and significant changes compared to t30 in the same group are indicated by #.
PaO2, PaCO2, arterial oxygen and carbon dioxide partial pressures; Lac, lactate concentration; Hb, total hemoglobin; BE, base excess; t30−150, timepoints in minutes after induction.