Table 5.
Bivariate analysis. Functional independence at 3 months and mortality.
| mRS ≤2, n = 128 | P | Mortality, n = 13 | p | |||
|---|---|---|---|---|---|---|
| Yes | No | Yes | No | |||
| n = 128 (%) | n = 61 (%) | n = 13 (%) | n = 176 (%) | |||
| Age, mean (SD) | 69.2 (13) | 70.3 (11) | 0.58 | 74.2 (7.9) | 69.2 (12) | 0.15 |
| Sex (male) | 63 (49) | 37 (61) | 0.16 | 8 (62) | 92 (52) | 0.58 |
| Arterial Hypertension | 87 (64) | 49 (80) | 0.08 | 11 (85) | 125 (85) | 0.36 |
| Diabetes mellitus | 21 (34) | 32 (25) | 0.22 | 3 (23) | 50 (28) | 1 |
| Dyslipidemia | 31 (51) | 47 (37) | 0.08 | 8 (62) | 70 (40) | 0.15 |
| Ischemic heart disease | 10 (16) | 11 (9) | 0.14 | 1 (8) | 20 (11) | 1 |
| Smoking | 19 (15) | 8 (13) | 0.93 | 0 (0) | 27 (15) | 0.11 |
| Oral anticoagulation | 36 (28) | 13 (21) | 0.38 | 5 (37) | 44 (25) | 0.33 |
| Atherothrombotic | 15 (12) | 12 (20) | 0.18 | 1 (8) | 26 (15) | 0.67 |
| Cardioembolic | 79 (62) | 32 (53) | 0.27 | 10 (77) | 101 (58) | 0.24 |
| Baseline NIHSS, median (IQ) | 16 (11–21) | 20 (15–25) | <0.0001 | 19 (17–23) | 17 (12–23) | 0.18 |
| Glucose mg/dL, mean (SD) | 130.9 (41) | 155.2 (78) | 0.026 | 136.8 (36) | 138.8 (58) | 0.9 |
| WBC/mm3, mean (SD) | 9,166 (2,712) | 10175.2 (3,646) | 0.059 | 8693.1 (3315.5) | 9547.4 (3050.3) | 0.33 |
| Neutrophils/mm3, mean (SD) | 6,321 (2,706) | 7,946 (3,806) | 0.004 | 6,831 (3,152) | 7,045 (3,759) | 0.82 |
| Lymphocytes/mm3, mean (SD) | 1,873 (1,017) | 1,537 (763) | 0.012 | 1,820 (960) | 1,016 (392) | <0.0001 |
| Ratio of neutrophils/lymphocytes, mean (SD) | 4.8 (4.1) | 7.1 (6.5) | 0.014 | 5.3 (4.7) | 8.9 (8.6) | 0.16 |
| Monocytes/mm3, mean (SD) | 460 (188) | 497 (235) | 0.25 | 471 (203) | 483 (231) | 0.84 |
| Platelets/mm3, mean (SD) | 216,271 (65,989) | 232,393 (103,787) | 0.2 | 222,498 (81,815) | 207,615 (54,768) | 0.52 |
| Fibrinogen mg/dL, mean (SD) | 338.5 (71) | 330.5 (75) | 0.49 | 317.4 (68) | 337.4 (73) | 0.36 |
| CRP * mg/dL, mean (SD) | 33.7 (36) | 60.3 (71) | 0.016 | 38 (35) | 42.8 (53) | 0.7 |
| Tandem occlusion | 16 (46) | 19 (54) | 0.004 | 2 (15) | 33 (19) | 1 |
| Distal occlusion (M2+M3) | 31 (24) | 7 (12) | 0.05 | 1 (8) | 37 (21) | 0.47 |
| ASPECTS, median (IQ) | 9 (8–10) | 8 (7–9) | <0.0001 | 8 (7–9) | 9 (8–10) | 0.21 |
| HMCA | 84 (66) | 32 (53) | 0.11 | 5 (39) | 111 (63) | 0.14 |
| HU pathological side, mean (SD) | 53.6 (9.5) | 53.5 (9) | 0.96 | 58.6 (9.7) | 53.2 (9.3) | 0.11 |
| HU ratio, mean (SD) | 1.4 (0.3) | 1.4 (0.4) | 0.68 | 1.6 (0.6) | 1.4 (0.3) | 0.49 |
| Mismatch**, mean (SD) | 83.4 (19) | 76.9 (20) | 0.05 | 78 (18.4) | 81.4 (19.4) | 0.63 |
| Intravenous thrombolysis | 51 (40) | 22 (36) | 0.64 | 5 (39) | 68 (39) | 1 |
| PH-2 | 0 | 4 (7) | 0.01 | 2 (15) | 2 (1) | 0.024 |
| Onset-CT, mean min (SD) | 321.3 (430.8) | 429.4 (550) | 0.14 | 292.5 (284) | 360.9 (485.1) | 0.62 |
| Onset-groin, mean min (SD) | 394.8 (444.7) | 579 (698.1) | 0.06 | 384.2 (323.8) | 459.4 (557.7) | 0.63 |
| Procedure time, mean min (SD) | 35.6 (25) | 39.8 (27) | 0.28 | 41.9 (35) | 35.6 (24) | 0.6 |
| Number of passes, mean (SD) | 1.7 (1.3) | 1.8 (1.1) | 0.71 | 1.8 (1) | 1.8 (1.2) | 0.97 |
| First pass effect | 28 (45.9) | 47 (36.7) | 0.27 | 6 (46.2) | 69 (39.2) | 0.77 |
| TICI 2B | 6 (4.7) | 15 (24.6) | <0.0001 | 5 (38.5) | 16 (9.1) | 0.007 |
| Stent retriever | 107 (84) | 48 (79) | 0.42 | 12 (92) | 143 (81) | 0.47 |
| Aspiration | 17 (13) | 10 (16) | 0.66 | 0 (0) | 27 (15) | 0.22 |
| FPC | 68 (53) | 32 (53) | 1 | 11 (85) | 89 (51) | 0.021 |
ASPECTS, Alberta Stroke Protocol Early CT Score; CRP, C-reactive protein; CT, computed tomography; DLP, dyslipidemia; DM, diabetes mellitus; FPC, fibrin-predominant clot; HBP, high blood pressure; HMCA, hyperdensity of the middle cerebral artery; HU, Hounsfield units; IQ, interquartile range; IV, intravenous; M2, 2nd segment of the middle cerebral artery; M3, 3rd segment of the middle cerebral artery; mRS, modified Rankin score; NIHSS, National Institute of Health Stroke Scale; OAC, oral anticoagulation; PH-2, type 2 parenchymal hemorrhagic transformation; SD, standard deviation; TICI, thrombolysis in cerebral infarction; WBC, white blood cell. The bold values indicated to highlight the results.