TABLE 4.
Baseline characteristics of patients with PD according to the levels of serum Lp-PLA2.
| Variables | Lp-PLA2 (ng/mL) |
P-value | |
| <200 (n = 29) | ≥200 (n = 29) | ||
| Gender (Male/Female) | 13/16 | 16/13 | 0.431 |
| Age (years) | 65.83 ± 9.11 | 64.66 ± 11.28 | 0.665 |
| Length of hospital stay (day) | 10.0 (5.5∼11.0) | 9.0 (7.0∼12.5) | 0.857 |
| Disease duration (years) | 3.0 (0.9∼4.0) | 5.0 (2.5∼8.0) | 0.122 |
| Family history [n(%)] | 1 (3.45) | 1 (3.45) | 1.000 |
| Dyslipidemia [n(%)] | 5 (17.24) | 1 (3.45) | 0.085 |
| Diabetes mellitus [n(%)] | 6 (20.69) | 6 (20.69) | 1.000 |
| Hypertension [n(%)] | 17 (58.62) | 17 (58.62) | 1.000 |
| Brain infarction [n(%)] | 9 (31.03) | 6 (20.69) | 0.368 |
| Smoking [n(%)] | 4 (13.79) | 4 (13.79) | 1.000 |
| Drinking [n(%)] | 1 (3.45) | 2 (6.90) | 0.553 |
| SBP/(mmHg) | 125 (117∼135) | 134 (121.5∼145.5) | 0.237 |
| DBP/(mmHg) | 84 (76∼91) | 84 (80∼90) | 0.901 |
| H&Y stage | 1.5 (1.0∼2.0) | 2.5 (2.0∼3.0) | <0.001 |
| ALT/(U/L) | 17 (10.5∼21.0) | 13 (9.0∼20.5) | 0.815 |
| AST/(U/L) | 20 (16.0∼23.5) | 18 (17.5∼22.0) | 0.656 |
| ALP/(U/L) | 73 (62.5∼83) | 69 (60∼79) | 0.641 |
| BUN/(mmol/L) | 4.42 (3.77∼6.26) | 4.76 (3.60∼5.26) | 0.446 |
| Cr/(μmol/L) | 69.35 (54.80∼85.35) | 62 (54.95∼71.90) | 0.932 |
| UA/(μmol/L) | 266.5 (233.4∼342.3) | 258.4 (197.3∼364.0) | 0.768 |
| Cys C/(mg/L) | 0.99 (0.88∼1.16) | 1.03 (0.89∼1.07) | 0.503 |
| Glu/(mmol/L) | 4.90 (4.43∼5.39) | 5.0 (4.61∼5.29) | 0.692 |
| TC/(mmol/L) | 4.47 (3.74∼4.98) | 4.23 (3.63∼4.85) | 0.988 |
| TG/(mmol/L) | 0.76 (0.61∼1.25) | 0.89 (0.74∼1.22) | 0.240 |
| HDL/(mmol/L) | 1.26 (1.07∼1.66) | 1.34 (1.13∼1.46) | 0.895 |
| LDL/(mmol/L) | 2.67 (1.95∼2.92) | 2.49 (1.90∼3.20) | 0.988 |
| CER/(mg/L) | 243.0 (232.5∼270.0) | 234.0 (221.0∼258.5) | 0.293 |
| SAA/(mg/L) | 7.1 (5.2∼10.8) | 6.7 (4.4∼10.9) | 0.519 |
| HCY/(μmol/L) | 13.6 (10.8∼18.5) | 14.6 (13.6∼18.7) | 0.437 |
| Lp-PLA2/(ng/mL) | 110 (100∼128) | 314 (271∼373) | <0.001 |