Table 1.
Clinical, histological and radiological characteristics of the patients as a function of pathologic response.
| Responders | Non-responders | All | p-value | |
|---|---|---|---|---|
| Number | 20 | 40 | 60 | — |
| Age (y) | 49.2 (±11.6) | 52,8 (±12.2) | 51.6 (±12.0) | 0.273 |
| ADC (x10^-6 mm^2/s) | 842 (±270) | 875 (±197) | 864 (±222) | 0,629 |
| PET SUV Max | 8.44 (±5.08) | 6.79 (±5.51) | 7.34 (±5.39) | 0,257 |
| Ki67 (%) | 39.7 (±23.0) | 20.0 (±11.3) | 26.6 (±18.5) | 0,0013 |
| PgR (%) | 12.3 (±23.9) | 34.6 (±33.9) | 27.2 (±37.5) | 0,0046 |
| ER (%) | 34.0 (±40.5) | 80.8 (±26.2) | 65.2 (±38.4) | 0,0001 |
| Grade | ||||
| 2 | 2 | 23 | 25 | 0,0006 |
| 3 | 18 | 17 | 35 | |
| HER2 | ||||
| Pos | 11 | 35 | 46 | 0,0088 |
| Neg | 9 | 5 | 14 | |
| Shape | ||||
| I | 8 | 27 | 35 | 0,0182 |
| O | 6 | 11 | 17 | |
| R | 6 | 2 | 8 | |
| Margin | ||||
| I | 16 | 19 | 35 | 0,0254 |
| S | 4 | 21 | 25 | |
| IntEnh | ||||
| E | 14 | 33 | 47 | 0,3654 |
| O | 1 | 3 | 4 | |
| RE | 5 | 4 | 9 | |
| Curve | ||||
| I | 0 | 3 | 3 | 0,6565 |
| II | 3 | 6 | 9 | |
| III | 17 | 31 | 48 | |
| Type | ||||
| MC | 6 | 18 | 24 | 0,4543 |
| MF | 5 | 6 | 11 | |
| U | 9 | 16 | 25 |
Data are presented either as mean ± sd or number of patients with relative percentage. Shape: (I)rregular/(O)val/(R)ound; Margin: (I)rregular/(S)piculated; IntEnh: H(e)terogeneous/H(o)mogeneous/(R)im (E)nhancement; Type: (M)ulti(c)entric/(M)ulti(f)ocal/(U)nifocal.