Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 20;12:589418. doi: 10.3389/fphar.2021.589418

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Satani, Zhang, Giridhar, Wewior, Cai, Aronowski and Savitz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Atorvastatin alters the secretome of monocytes from healthy controls and stroke patients after 24 h of exposure. Atorvastatin increased IL-1RA and TNF-α secretion from stroke patient derived monocytes as well as healthy control monocytes at 8 µM dose. Atorvastatin had no effect on secretions of IL-8, IL-1β and MCP-1 from stroke monocytes, but decreased the MCP-1 secretion from healthy control monocytes. Significance is shown by *p < 0.05.