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. 2021 Apr 20;12:612501. doi: 10.3389/fgene.2021.612501

FIGURE 2.

FIGURE 2

Plasma levels of the studied mediators in obese patients with type 2 diabetes mellitus (T2DM) before and after laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB). (A) Plasma level of C-peptide. (B) Plasma level of ghrelin. (C) Plasma level of GIP. (D) Plasma level of GLP-1. (E) Plasma level of insulin. (F) Plasma level of resistin. (G) Plasma level of leptin. (H) Plasma level of visfatin. (I) Plasma level of PAI-1. (J) Plasma level of glucagon. ∗p < 0.05; differences in significance level were determined using one-way ANOVA. 1 – healthy volunteers before breakfast; 2 – healthy volunteers after breakfast; 3 – obese patient without T2DM before breakfast; 4 – obese patient without T2DM after breakfast; 5 – obese patient with T2DM before breakfast; 6 – obese patient with T2DM after breakfast; 7 – 6 months after LSG before breakfast; 8 – 6 months after LSG after breakfast; 9 – 6 months after RYGB before breakfast; 10 – 6 months after RYGB after breakfast.