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. 2021 Apr 20;12:650605. doi: 10.3389/fphar.2021.650605

TABLE 1.

Clinical Manifestations and Autoantibodies Levels in SSc Patients

Clinical Manifestations Total lcSSc dcSSc ssSSc
n = 83 n = 64 n = 17 n = 2
Raynaud 82 (99) 64 (100) 17 (100) 1 (50)
Skin Fibrosis 72 (87) 55 (86) 17 (100) 0 (0)
Puffy fingers/hands 37 (45) 31 (48) 6 (35) 0 (0)
Microstomy 19 (23) 12 (19) 7 (43) 0 (0)
Tendinous retractions 48 (58) 23 (36) 15 (93) 0 (0)
Telangiectasia 62 (75) 49 (76) 12 (70) 1 (50)
Calcinosis 20 (24) 15 (23) 5 (29) 0 (0)
Pitting scars 30 (36) 18 (28) 12 (70) 0 (0)
Digital ulcers 22 (26) 14 (22) 8 (47) 0 (0)
Digital amputation 6 (7) 4 (6) 2 (12) 0 (0)
Disphagia 31 (37) 23 (36) 7 (41) 1 (50)
Diarrhea 15 (18) 13 (20) 2 (12) 0 (0)
Constipation 22 (26) 19 (29) 3 (18) 0 (0)
ILD 28 (34) 18 (28) 9 (53) 1 (50)
PHT 18 (22) 13 (20) 3 (18) 2 (100)
Arthritis 11 (13) 7 (11) 3 (18) 1 (50)
Muscular weakness 5 (6) 3 (5) 1 (6) 1 (50)
Gastroesophageal reflux 36 (43) 26 (40) 9 (53) 1 (50)
Autoantibodies
 ANA 82 (99) 63 (98) 17 (100) 2 (100)
 ACA 44 (53) 42 (66) 2 (12) 0 (0)
 Scl-70 20 (24) 8 (12) 11 (65) 1 (50)

Data are expressed as n (%). ILD, Intersticial Lung Disease; PHT, Pulmonary Hypertension. ANA, Antinuclear antibodies; ACA, anticentromere antibodies; Scl 70, anti topoisomerase 1.