TABLE 1.
Clinical Manifestations | Total | lcSSc | dcSSc | ssSSc |
---|---|---|---|---|
n = 83 | n = 64 | n = 17 | n = 2 | |
Raynaud | 82 (99) | 64 (100) | 17 (100) | 1 (50) |
Skin Fibrosis | 72 (87) | 55 (86) | 17 (100) | 0 (0) |
Puffy fingers/hands | 37 (45) | 31 (48) | 6 (35) | 0 (0) |
Microstomy | 19 (23) | 12 (19) | 7 (43) | 0 (0) |
Tendinous retractions | 48 (58) | 23 (36) | 15 (93) | 0 (0) |
Telangiectasia | 62 (75) | 49 (76) | 12 (70) | 1 (50) |
Calcinosis | 20 (24) | 15 (23) | 5 (29) | 0 (0) |
Pitting scars | 30 (36) | 18 (28) | 12 (70) | 0 (0) |
Digital ulcers | 22 (26) | 14 (22) | 8 (47) | 0 (0) |
Digital amputation | 6 (7) | 4 (6) | 2 (12) | 0 (0) |
Disphagia | 31 (37) | 23 (36) | 7 (41) | 1 (50) |
Diarrhea | 15 (18) | 13 (20) | 2 (12) | 0 (0) |
Constipation | 22 (26) | 19 (29) | 3 (18) | 0 (0) |
ILD | 28 (34) | 18 (28) | 9 (53) | 1 (50) |
PHT | 18 (22) | 13 (20) | 3 (18) | 2 (100) |
Arthritis | 11 (13) | 7 (11) | 3 (18) | 1 (50) |
Muscular weakness | 5 (6) | 3 (5) | 1 (6) | 1 (50) |
Gastroesophageal reflux | 36 (43) | 26 (40) | 9 (53) | 1 (50) |
Autoantibodies | ||||
ANA | 82 (99) | 63 (98) | 17 (100) | 2 (100) |
ACA | 44 (53) | 42 (66) | 2 (12) | 0 (0) |
Scl-70 | 20 (24) | 8 (12) | 11 (65) | 1 (50) |
Data are expressed as n (%). ILD, Intersticial Lung Disease; PHT, Pulmonary Hypertension. ANA, Antinuclear antibodies; ACA, anticentromere antibodies; Scl 70, anti topoisomerase 1.