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. 2021 May 3;4(2):e274. doi: 10.1002/hsr2.274

TABLE 2.

Effect size and test of heterogeneity for the case fatality rate (CFR) by region, population median age (median value), and tests per thousand population (median value)

Statistics Region Test for Subgroup differences Overall
Africa Asia Europe North America Oceania South America
Effect Size (95% CI)

7.11

(6.38, 7.91)

2.49

(2.08, 2.94)

2.82

(1.98, 3.81)

3.40

(2.81, 4.04)

0.20

(0.02, 0.51)

2.89

(2.03, 3.89)

254.44

(P‐value = .00)

2.67

(2.25, 3.13)

I 2 statistic 99.66% 99.98% 99.84% 32.87% 99.69% 99.95%
Cochran's Q statistics 315 324.53
n (sample = 158) 1 69 60 15 4 9 158
Total tests per thousand population
Less than or equal to 111.16 tests Greater than 111.16 tests Overall
Effect size (95% CI) 3.15 (2.57, 3.79) 2.16 (1.57, 2.83)

5.14

(P value = .02)

2.68 (2.25, 3.14)
I 2 statistic 99.90% 99.97% 99.95%
Cochran's Q statistics 315 324.53
n (sample = 157) 87 70 157
Population Median Age Category
Less than or equal to 38.7 years Greater than 38.7 years Overall
Effect size (95% CI) 2.27 (1.85, 2.74) 3.13 (2.44, 3.91)

4.30

(P value = .04)

2.67 (2.25, 3.13)
I 2 statistic 99.80% 99.97% 99.95%
Cochran's Q statistics 315 324.53
n (sample = 158) 82 76 158